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Transfer to ICU

You are the receiving provider in the ICU for Mrs. Castillo. You received the transfer report, and know that she was found down at home by a friend and brought to the ED for further evaluation. Her past medical history is significant for hypertension (though she is currently hypotensive), type 2 DM, osteoporosis, hyperlipidemia, restless leg syndrome, and recent falls.


On arrival to the ED, she was found to have respiratory failure and was intubated. She received a bolus of 1 L of NS for hypotension in the ED. Radiologic exams were significant for a right acute on chronic subdural hematoma (SDH) without shift, and multiple old and new rib fractures. Her spine CT was negative. Neurosurgery has been consulted for the SDH and deemed she will not benefit from surgery at this time. She received fentanyl for pain. She has 2 adult children but they have not been reached at this time. Unclear if advance directives exist.

Click the pictures below to see the most recent lab results:



Blood Tests



Urinalysis



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Initial exam in ICU

The ICU team re-examines the patient on arrival and finds:

  1. Gen: Thin, frail, elderly female seen in bed; grimacing to chest palpation, guarding her chest; otherwise calm, resting
  2. Current VS: BP 100/50 mmHg; HR 110 BPM; RR 18 BPM; Temp 97.0 F; SpO2 96%; Weight 55 kg
  3. Vent settings: Endotracheally intubated; Volume Control AC 18; 100% FiO2; TV 450 mL; PEEP 5 cm H2O
  4. Neuro: GCS is Eye 3/Verbal 1T/Motor 6 (10T); PERRL; strength 4/5 throughout; reflexes wnl for age
  5. CV: Sinus tachycardia; S1/S2 auscultated, no murmurs, rubs or gallops
  6. Resp: Bilateral breath sounds equal but diminished in bases; otherwise clear to auscultation
  7. GI: + BS; abd soft/nontender
  8. GU: Foley cath intact; urine output 50 mL in last hour
  9. Skin: Oral mucosa pink but dry; skin friable, decreased turgor
  10. Notable that there is no family at bedside and they have not yet been located to discuss Mrs. Castillo’s current status and ongoing care.

Type your current problem list for Mrs. Castillo in the box below.






  1. SDH
  2. Hyponatremia, unknown etiology
  3. Altered mental status
  4. Unclear advance directive/durable power of attorney
  5. Type 2 diabetes, hyperglycemia
  6. Hypotensive, history of hypertension
  7. Respiratory failure requiring mechanical ventilation
  8. Chronic kidney disease, stage 3A
  9. Rib fractures; new and old
  10. Pain
  11. Fall risk
  12. Possible elder abuse
  13. Currently unable to each family
  14. Unclear capacity for continued independent living; discharge disposition

1Advanced trauma life support (ATLS®): the ninth edition. ATLS Subcommittee et al. J Trauma AcuteCare Surg. (2013).



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Admitting orders

Admit to ICU
Dx: SDH, Hyponatremia, Respiratory Failure

As the Physician or Advanced Practice Provider reviewing the expert problem list, which nursing care, diet, and activity orders should be included in the admitting orders for Mrs. Castillo? Type your answer in the box below.






Nursing Care: ICU bundle for vital signs, I&O and provider notification; sequential compression devices for DVT prophylaxis
Diet: NPO; place feeding tube, KUB to check placement
Activity: Elevate HOB 30-45 degrees; fall precautions


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Admitting orders – Labs & Diagnostic Studies

In addition to the AM labs (Basic Metabolic Panel, H&H) what labs should be on the admitting orders?

  • Finger Stick Blood Sugar (FSBS) every 2 hours
  • Serum sodium every 2 hours
  • Calcium, albumin with next blood draw
  • ABG 30 minutes after vent change

Green answers are correct.
Red answers are not correct.




Which of the following diagnostic studies should be included on admitting orders?

  • Head MRI in a.m.
  • Repeat Head CT in a.m.
  • Cervical spine x-ray

Green answers are correct.
Red answers are not correct.






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Admitting orders – Consults

It is important to collaborate with the following providers in Mrs. Castillo’s care. Click the boxes below to see the reasons for each consult.


Pharmacist



Respiratory Therapist




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Admitting Orders - Medications

What medication should be ordered for Mrs. Castillo?

  • Acetaminophen 650 mg PR/per NGT every 4 hours prn for T >38.5; not to exceed 3g/day
  • Fentanyl 25-50 mcg IV every 30 min prn for pain
  • Midazolam 2 mg IV every 3 hours prn agitation
  • Pantoprazole 40 mg IV daily
  • Insulin via continuous infusion (refer to insulin protocol)
  • Keppra 1000 mg IV every 12 hours x 7 days for seizure prophylaxis - consult pharmacist for renal dosing
  • Propofol for sedation (refer to analgesia sedation protocol)
  • Meperidine 25 mg IM every 4 hours prn pain
  • Heparin 5000 units subcutaneously every 12 hours
  • Enoxaparin 30 mg subcutaneously every 12 hours
  • Haloperidol 5 mg IV every 1 hour prn agitation
  • Norepinephrine 5 mg/min titrate to SBP greater than 120 mm Hg

Green answers are correct.
Red answers are not correct.



Clinical Pearl






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Current Medications

Here is a list of the medications Mrs. Castillo was taking before she was admitted to the hospital. Please mark which medications she should continue at this point.

  • Aspirin EC 81 mg daily
  • Simvastatin 20 mg at bedtime
  • Propranolol LA 120 mg daily
  • Ropinirole 3 mg before bedtime
  • Tylenol PM - suggested dose 2 tabs qhs prn.
         Contains APAP 500 mg and diphenhydramine 25 mg per tablet
  • Metformin 1000 mg twice daily
  • Alendronate 70 mg every week on Tuesday
  • Calcium carbonate with vitamin D 500 mg/400 IU 1 tablet twice daily
  • Enalapril 5 mg twice daily

Green answers are correct.
Red answers are not correct.




Recommendation – do not continue any of Mrs. Castillo’s original medications at this time.

Clinical Pearl...



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Would you recommend ICP monitoring at this time?

  • Yes
  • No




ICP monitoring is not indicated for Mrs. Castillo at this time. Recommendations are that persons with SDH who have a GCS score less than 9 should undergo intracranial pressure (ICP) monitoring. Click here for the latest guidelines.

If Mrs. Castillo’s neurologic status changes or her repeat head CT indicates worsening SDH or new cerebral edema, placement of ICP monitor may be warranted.


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Nursing Orders

The receiving nurse requests an order for bilateral wrist restraints as the patient is intubated.

Are restraints appropriate at this time for Mrs. Castillo?

  • Yes
  • No




NO. This order is not warranted at this time as patient is not interfering with therapies.


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New test results

    New lab tests are available!
  • Serum Na+ 111 mEq/L
  • Serum Osmolality 256 mOsm/kg
  • Urine SG 1.030
  • Urine Na+ 89 mmoL/L
  • Urine Osmolality 588 mOsm/kg

Current vital signs:
BP 92/48 mmHg; HR 122 BPM; RR 18 BPM; SpO2 97%

Based on this new information, what is the patient’s volume status?

  • Hypovolemic
  • Euvolemic
  • Hypervolemic

Green answers are correct.
Red answers are not correct.




What is the likely cause of the hyponatremia?

  • Syndrome of Inappropriate Antidiuretic Hormone (SIADH)
  • Cerebral Salt Wasting
  • Pseudohyponatremia
  • Diuretic-induced hyponatremia

Green answers are correct.
Red answers are not correct.




Clinical Pearl: CSW vs. SIADH





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CSWS management

What are your next steps to manage Mrs. Castillo’s cerebral salt wasting? Type your answer in the box below.






  • Begin administering normal saline at rate of 60 mL/h
  • Continue to monitor serum sodium levels every 2 hours
Clinical Pearl: Correcting Hyponatremia

The short-term goal for correcting hyponatremia is to achieve sodium concentration in the range of 120-125 mEq/L or resolution of symptoms. Sodium should not be corrected by more than 10 mEq/L per day with complete correction over 48-96 hours. Correction should be done slowly to avoid central pontine myelinolysis.


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ICU Complications

What complications associated with ICU admission should be considered?

Which of these complications are currently being addressed by the management plan?

Use the chart below to mark your answers. Click below each column to see the correct answers.

    Complications to Consider Currently Addressed
    Risk for malnutrition
  • Risk for DVT
  • Risk for stress ulcer
  • Risk for delirium (age, sleep issues, meds, etc).
  • Risk for infection (UTI; Pneumonia)
  • Inadequate sedation/analgesia
  • Risk for falls
  • Glycemic control
  • Risk for skin breakdown


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Delirium Risk

What should be added to the plan of care in order to minimize risk of delirium for Mrs. Castillo?

Check all the boxes that apply:

  • Assess for delirium using the CAM-ICU
  • Assess for level of sedation using the RASS or other validated scale
  • Assess for any sensory assistive devices (hearing aid, glasses)
         used at home and ensure available
  • Exposure to natural lighting during the daytime hours
  • Minimize light/noise/interventions at night to maximize potential for sleep
  • PT consult for mobilization
  • Reassess need for invasive tubes and lines on daily rounds
         (to include spontaneous awakening/breathing trials)
  • Use of restraints at night but not during the day
  • Support orientation to day/time/place with visible clock,
         whiteboard with date and care goals
  • Prophylactic use of antipsychotic medication
  • Haloperidol 10 mg IV every 1 hour as needed for agitation

Green answers are correct.
Red answers are not correct.






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Minimizing risk of infection and skin breakdown

The ICU nurse approaches the team and asks for additional orders to the plan of care to minimize risk of infection and skin breakdown. What orders are needed?

  • Oral care protocol for VAP prevention
  • Turning every 2 hours
  • Egg crate mattress
  • Air fluidized specialty bed
  • Nutrition assessment and request for nutrition orders

Green answers are correct.
Red answers are not correct.






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Geriatric Syndromes

In addition to pain, falls, and delirium, what geriatric syndromes are actual or potential problems for Mrs. Castillo at this time?

  • Constipation
  • Dementia
  • Depression
  • Frailty
  • Incontinence

Green answers are correct.
Red answers are not correct.




Clinical Pearl...

Mrs. Castillo is at increased risk of constipation due to normal aging changes in GI motility, her reduced mobility and opioid regimen. It would be important for the team to assess frequency of BMs at home, any recent changes, and place Mrs. Castillo on a bowel regimen.


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Additional concerns

What ongoing concerns should the team have about Mrs. Castillo’s history and presentation that warrant follow up at this point? Type your answer in the box below.






  • History of multiple falls
  • Multiple old and new rib fractures
  • Inability to locate family
  • Ongoing capacity for independent living
Clinical Pearl...

Your concerns over falls and rib fractures should trigger an evaluation of home safety, assessment of Mrs. Castillo’s capacity for continued independent living, and raise a concern for possible abuse and/or neglect. Social work, PT/OT, and other team members are appropriate to involve in these assessments. These consults should be ordered immediately because they directly impact the discharge plan and are critical to maintaining the patient’s safety both in and out of the hospital. These team members will gather as much information as possible from Mrs. Castillo, Mrs. Castillo’s family members and friends, medical records and other care providers.


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Arrival of daughter at ICU

Mrs. Castillo’s daughter, Angelina, arrives at the hospital.

What should the team discuss with her at this time? Type your answer in the box below.






  • Update Angelina on her mother’s condition
  • Clarify:
    • medical history, confirm primary care provider
    • use of complementary and alternative approaches to manage health
    • home situation (safety, independent living, family involvement)
    • advance directives and any medical power of attorney
    • cultural and spiritual values
  • Identify goals of care


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Conversation between Angelina and provider


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Next steps

What would the team’s best action be in response to this new information?

Check all that apply:

  • Contact Dr. Kim’s office to notify of patient’s admission
  • Consult spiritual care
  • Encourage daughter to notify parish office of patient admission to the hospital
  • Continue to work with daughter and family to clarify advance directives and goals of care
  • Make sure referral to SW is complete in order to further assess home safety

Green answers are correct.
Red answers are not correct.





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Evening Rounds

Four hours after admission to the ICU, the team begins evening rounds. During the assessment they find Mrs. Castillo interactive and oriented to name and place, and following simple one-step commands. She is tolerating the ventilator. When asked if she is in pain, she gestures to her back and left side. She has been receiving pain medications every 1-2 hours with some relief, but remains restless with occasional facial grimacing.

What are alternative strategies to pain management you should explore in collaboration with the pain management service for this patient? Check all that apply.

  • Change the ordered medication to morphine
  • Consider changing route of analgesia administration to epidural or intrathecal
  • Consider beginning dexmedetomidine drip
  • Consider nerve block techniques with local anesthetics
  • Increase dose of fentanyl to 50 mcg IV every hour as needed for pain

Green answers are correct.
Red answers are not correct.




Clinical Pearl: Pain Management

If pain is related to rib fractures, using alternate routes of administration of drugs (i.e., nerve blocks with local anesthetics) can allow for patient comfort, minimize the side effects of systemic medications like opioids, and allow for higher level of alertness with more comfortable ventilator weaning. Pain service would need to be consulted for catheter placement.


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Sign out

What treatment goals should be communicated in the provider handoff at the end of the shift? Type your answer in the box below.






  • Correction of hyponatremia
  • Pain management
  • Initiate nutrition once KUB results are available and tube placement is confirmed
  • Maintain glucose in target range with insulin drip
  • Ventilatory support – assess for possible extubation tomorrow

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Hospital Day 2; 5 a.m.

    Overnight your colleague managed Mrs. Castillo. The focus was on managing her pain, the hyponatremia, beginning nutrition with tube feedings, and adjusting the insulin drip and ventilator support. The team is beginning AM rounds and assesses Mrs. Castillo and notes the below:
  • Subjective: Shakes her head “No” when asked “Are you in pain?”
  • Objective: BP 113/77, HR 88, RR 20, T 98.2 F, SpO2 98%
  • Vent settings AC 18; 40% FiO2; TV 450; PEEP 5, Peak/plateau pressures 30/15
  • Sodium level has now risen to 121 mEq/L
  • Hemoglobin (Hgb) level is 7.6 g/dL and Hematocrit (Hct) is 30% (both trending down); MCV 84 fL/red cell (reference range 80-96)
  • Repeat Head CT: unchanged

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Mrs. Castillo’s hemoglobin and hematocrit are low. Which of the following differential diagnoses is most likely?

  • Anemia of chronic disease
  • Bleeding
  • Hemodilution
  • Infection
  • Iron or B12 deficiency
  • Malnutrition
  • Neoplasm
  • Hemolysis

Green answers are correct.
Red answers are not correct.




Clinical Pearl

Hemorrhage should always be considered in the differential diagnosis. Systemic symptoms of bleeding would include changes in vital signs (tachycardia, hypotension) and pallor. However, Mrs. Castillo’s presentation does not match this presentation.


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What are the actions to take at this point in response to the lowered Hct?

  • Move to hypertonic saline to reduce total fluid administration required for sodium correction
  • Blood transfusion
  • Repeat H&H per protocol
  • Begin daily FeSO4 supplementation

Green answers are correct.
Red answers are not correct.





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Mrs. Castillo’s current problem list is below. Which 4 problems are the priority at this time?

    Priority Problems
    Anemia, hemodilutional
  • Cerebral salt wasting
  • Respiratory failure, resolving
  • Type 2 DM, hyperglycemia
  • Hypotension
  • CKD
  • Rib fractures (new and old)
  • Pain
  • Glycemic control
  • Subdural hematoma
  • Fall risk
  • Unable to reach family
  • Green answers are correct.
    Red answers are not correct.



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Mrs. Castillo’s current problem list is below. Mark the problems that are now resolved.

    Priority Problems
    Anemia, hemodilutional
  • Cerebral salt wasting
  • Respiratory failure, resolving
  • Type 2 DM, hyperglycemia
  • Hypotension
  • CKD
  • Rib fractures (new and old)
  • Pain
  • Glycemic control
  • Subdural hematoma
  • Fall risk
  • Unable to reach family
  • Green answers are correct.
    Red answers are not correct.


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Hospital Day 2; 12 p.m.

Family is updated on patient’s status/plans during morning multidisciplinary rounds.

Due to issues on Hospital Day 1 with pain control, an order was written to check with provider first before spontaneous breathing trial (SBT). You are now approached by the respiratory therapist who asks if there is any reason why a SBT should not be attempted with Mrs. Castillo.

Which of the following are indicators that Mrs. Castillo is suitable for weaning at the present time (check all that apply)?

  • Patient is interactive
  • Pain is well controlled
  • Stable systolic blood pressure
  • FiO2 currently at 40%
  • Initiating spontaneous breaths
  • PEEP currently at 5 cm H2O
  • Adequate SpO2 (98%)
  • Hemoglobin level > 7 g/dL
  • Adequate ventilation based on ABG

Green answers are correct.
Red answers are not correct.





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Following a successful SBT, Mrs. Castillo was able to be extubated.

Following extubation, she is alert and oriented X3, but has deficits in short-term memory. She was ambulated OOB to chair, but was easily fatigued. The social worker interviews the patient, and the family is determined to be safe and supportive. Mrs. Castillo confirms that her goal is to continue living independently. Therefore, she will need to maintain and regain optimal function.

What consults would be useful to obtain now to assist with her management directed towards this goal? (Check all that apply)

  • Physical Medicine and Rehabilitation
  • Pulmonary Rehabilitation
  • Speech Therapy

Green answers are correct.
Red answers are not correct.





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Mrs. Castillo is stable overnight and plans are made to transfer her to the hospitalist service and the medicine acute care floor.

The following areas of information are included in the transfer note. Use the box below to write the areas of information that are missing from the note.

  • Date of Admission to the ICU
  • Date of Discharge
  • Admitting Diagnosis
  • Discharge Diagnosis
  • Secondary Diagnoses
  • Family/Social History
  • Procedures
  • Consultations
  • ICU Course
  • Physical Exam:
  • Condition
  • Disposition
  • Current Medications
  • Pending Studies
  • Assessment/Plan
  • Accepting Provider






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Following her transfer to the medicine floor, Mrs. Castillo continued to stabilize medically. Physical therapy continued to work with Mrs. Castillo regarding mobility, balance and conditioning. In addition, speech therapy was started to assist with cognitive strategies. Mrs. Castillo was ultimately discharged to rehabilitation for continued therapy.

You have now completed the case study.
Please click on the link below to provide feedback on your experience.

Older Adult Found Down Evaluation


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Respiratory Therapy:


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Social Work:

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Minimizing the Risk of Infection: Guidelines and References

Preventing ventilator-associated pneumonia (VAP)

Coffin SE, et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals. Infect Control Hosp Epidemiol 2008 Oct;29 Suppl 1:S31-40.


AACN Practice Alert - Ventilator Associated
Pneumonia:


Preventing catheter-associated urinary tract infection (CAUTI)

Gould CV, et al. Healthcare Infection Control Practices Advisory Committee (HICPAC). Guideline for prevention of catheter-associated urinary tract infections 2009. Atlanta (GA): Centers for Disease Control and Prevention (CDC); 2009.


Preventing central line-associated bloodstream infection (CLABSI)

Marschall J, et al. Strategies to prevent central line-associated bloodstream infections in acute care hospitals. Infect Control Hosp Epidemiol 2008 Oct;29 Suppl 1:S22-30.

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Blood Tests

Blood Alcohol Level: 0
INR: 1.0 (normal)
PTT: 35 seconds

CBC:
Hgb 9.9 g/dL
Hct 38%
RBCs 4.4 x 106 cells/mcL
Platelets 152,000/mm3
WBC 12,000 cells/mcL
   Neutrophils 70% - Hi
   Lymphocytes 23%
   Monocytes 6%
   Eosinophils 1%
   Basophils 0.2%

BMP:
BUN 27 mg/dL
CO2 22 mmol/L
Creatinine 0.95 mg/dL
BUN/Creatinine Ratio: 28 - Hi
Glucose 310 mg/dL - Hi
Sodium 112 mEq/L - Lo
Chloride 85 mEq/L
Potassium 4.3 mmol/L

GFR calculated: 57.7 mL/min/1.73 m2 - Lo

Troponin: 0.01 ng/mL negative CK: 50 U/L


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Urinalysis

U/A- wnl, except for + protein
Urine Toxicology Screen-negative

Pending labs:

Serum Na+, Serum Osmolality, Urine specific gravity, Urine Na+, Urine Osmolality

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Radiology


Multiple left-sided rib fractures. Most of these appear to be chronic and healed; however, there are acute-subacute appearing fractures of the anterolateral aspect of the left 4th and 5th ribs. Ununited chronic fracture of the lateral aspect of the left 6th rib.




Spine CT: No fractures.




Head CT: 3mm right acute on chronic holohemispheric subdural hematoma without shift. No noted skull fractures.

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Pharmacy Consult

What should be ordered for this patient?

  • Fentanyl 25 mcg IV
  • Morphine sulfate 1mg IV
  • Meperidine 25 mg IM
  • Midazolam 0.5 mg IV

Green answers are correct.
Red answers are not correct.






Clinical Pearl...

Listen to the pharmacist’s rationale for drug choice




Photo courtesy of UW Medicine.

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Neurosurgery Consult



Clinical Pearl...

Aspirin therapy, such as Mrs. Castillo was receiving, disrupts platelet function by inhibiting COX1 for the life of the platelet (~7-10 days). Presently, platelet transfusion for patients receiving antiplatelet agents, such as aspirin, is controversial and requires further study. A summary of work in this area is provided in the link below.





"Platelets2". Licensed under GFDL via Wikimedia Commons